Disease Information Center

The generally acceptable measurement error range for home glucose meters is ±15%.
For example, if the hospital lab test value is 10.0 mmol/L, a glucose meter reading between 8.5 and 11.5 mmol/L is considered within the acceptable range.
Calculation formula:
10.0 ×（100% ± 15%）= [8.5 ~ 11.5] mmol/L

• Fasting (at least 8 hours without eating): 3.9–6.1 mmol/L

• 1-hour postprandial (after meal): 6.7–9.4 mmol/L (typically not exceeding 11.1)

• 2-hour postprandial: ≤7.8 mmol/L

• Postprandial timing starts from the first bite of food. If you have individualized medical instructions, please follow them strictly.

• Fasting: <5.3 mmol/L (at least 8 hours without eating)

• 2-hour postprandial: <6.7 mmol/L (timing starts from the first bite of food)

• Blood glucose control during pregnancy is quite specific; it is essential to follow your doctor's individualized guidance.

Currently, glucose test strips on the market primarily use the Glucose Oxidase (GOD) method and the Glucose Dehydrogenase (GDH) method. They differ in measurement principle, stability, and resistance to interference.

Glucose Oxidase (GOD) Principle: Glucose oxidase reacts with glucose in the blood in an oxidation reaction, producing hydrogen peroxide, which is then detected by an electrochemical sensor.

• Advantages:Mature technology, widely used; fast detection speed, suitable for daily monitoring for most people.

• Limitations:Susceptible to external oxygen concentration, temperature, and humidity changes. If test strips are exposed for too long or become damp, accuracy may be affected.

Glucose Dehydrogenase (GDH) Principle: Glucose dehydrogenase catalyzes glucose to directly generate electrons, allowing glucose concentration to be measured electrochemically without relying on oxygen participation in the reaction.

• Advantages:Strong resistance to oxygen interference, less affected by external oxygen or humidity, high stability; wider applicable hematocrit (HCT) range, more suitable for pregnant women, anemic individuals, or those with significant HCT fluctuations.

• Limitations:Relatively complex production process; some GDH subtypes (e.g., GDH-PQQ) may cross-react with other sugars (e.g., maltose, galactose).

Testing frequency should be determined by your doctor based on your individual condition. The following are common references:

• For poor glucose control: Monitor 3 days per week, 5-7 times per day (fasting, 2 hours after each meal, bedtime, and during the night).

• For stable glucose control: Monitor 3 days per week, 2 times per day (fasting and postprandial).

• For insulin users: Recommended 2-5 times daily (pre-meal and bedtime).

• For those using only oral medication or lifestyle intervention: 2-4 times per week (postprandial glucose).

• Before measurement, it is recommended that both the meter and test strips be placed in an environment between 5°C and 40°C for at least 30 minutes to allow them to reach the same temperature.

• Only begin blood sampling after the meter has completed its power-on self-test and the blood drop symbol appears on the screen.

• The sampling site must be thoroughly cleaned. Disinfection with an alcohol swab is recommended; avoid using iodine-based disinfectants.

• Warm and massage the finger before pricking to ensure a good blood flow. Aim for a single prick that produces a full, rounded drop of blood. Avoid excessive squeezing, as this can dilute the blood with tissue fluid and affect the result.

A single high or low reading is not sufficient to indicate a problem. The overall trend should be judged based on multiple measurements over a continuous period. Also, note the short-term effects of diet, exercise, mood, and alcohol consumption on blood glucose.

The typical measuring range for home glucose meters is 0.6–33.3 mmol/L.

The suitable operating temperature for a glucose meter is 5°C–40°C. In winter, you can warm the meter and strips by keeping them close to your body before use. Do not place them directly on a heater.

Test strips should be stored at 4°C–30℃, protected from light and moisture. After opening the vial, minimize exposure time. Avoid storing them near volatile substances like alcohol, cosmetics, or perfume.

All Yuwell glucose meters use the electrochemical detection principle.

• Electrochemical Method:Glucose in the blood undergoes an electrochemical reaction with glucose oxidase, generating an electric current that is converted into a blood glucose value.

• Difference between Photochemical and Electrochemical Methods:Photochemistry studies chemical changes caused by the interaction of light and matter, often used in laboratory research. Electrochemical methods detect reactions between electrodes and electrolytes, making them suitable for fast and convenient clinical and home glucose testing.

• Home glucose meters detect glucose concentration in capillary whole blood.

• Hospital lab analyzers typically measure glucose in venous plasma or serum.

• Continuous Glucose Monitors (CGM) can detect glucose concentration in interstitial fluid.
  

• The distribution of glucose varies in different parts of the body and different body fluids, hence the results from these methods are not identical.

Glucose meters test capillary whole blood glucose, while hospitals typically test venous plasma or serum glucose. The chemical principles and instruments used are different, leading to variations in results. As long as the difference falls within the acceptable error range, it is considered normal.

Most current glucose meters use the "glucose oxidase electrode method" or "glucose dehydrogenase electrode method." While fast and convenient, these methods can yield variations of up to ±15% even for the same drop of blood at the same time, which is within the acceptable range.

Different brands of glucose meters use different test strip enzymes and electrode components, leading to variations in their detection response to glucose, which results in a certain degree of deviation between readings.

Repeatedly squeezing the same fingertip for blood can change blood composition (e.g., the ratio of serum to blood cells), affecting glucose concentration. Slight differences in the meter's circuit state upon each startup can also introduce minor errors. However, if the readings are within the acceptable error range, they are considered normal.

Proper Blood Sampling: Before pricking, let your arm hang down, rub your hands, and ensure fingertips are warm and充血; obtain a full, rounded drop of blood and avoid repeated squeezing.

• Proper Strip Storage:Keep strips sealed, protected from light and moisture. Do not use expired strips. Avoid touching the test area when handling strips.

• Regular Maintenance:Clean the glucose meter regularly, keep the sensor area free from contamination. Do not clean optical components with alcohol or organic solvents.

• Ensure Adequate Power:Low battery power can affect readings. Replace or recharge batteries promptly when power is low.

• Regular Calibration:Perform regular quality control using control solution. If deviations exceed 15%, contact the manufacturer for calibration.

• Be Aware of Medication Effects:Strong reducing agents like Vitamin C can interfere with results. If necessary, pause such medications before testing.

BGM meters of different brands and models must be used with their specific, matching test strips. Using strips from other brands is not recommended.

Store at 5°C–40℃, in a cool, dry place. Avoid prolonged exposure with the cap off. Keep away from volatile substances (e.g., alcohol, perfume).

Ensure an adequate blood drop is obtained. Position the strip so the blood is drawn into the center of the strip's sampling channel. Avoid letting blood touch only the edges of the channel, which can lead to insufficient filling.

Both home glucose meters and hospital equipment require regular quality control to ensure readings remain within the acceptable range. If there is doubt about a value, the hospital venous blood biochemical test result should be considered the benchmark, and judgment should be made in conjunction with a doctor's advice.

The human body's blood glucose levels are inherently dynamic and constantly changing. They are influenced by various factors such as mood, diet, hydration, and exercise. Levels may be lower when you are calm and can rise when you are excited or stressed. Therefore, as long as there are no abnormal sharp fluctuations, variations in glucose readings at different times are within the normal range.

Common reasons include:

• Testing the same drop of blood twice:Blood exposed to air becomes oxidized, altering its actual composition, which often leads to a different result on the second test.

• Drawing blood consecutively from the same puncture site: After the first measurement, interstitial fluid may seep into the puncture site. The blood sample drawn second may contain more of this fluid, leading to a lower reading. Excessive squeezing can exacerbate this effect.

• Comparing blood from different hands or fingers at the same time: Blood glucose is a real-time fluctuating indicator, so this type of comparison is not recommended. If verification is needed, bring your glucose meter to the hospital to compare its reading with a venous blood biochemical test result.

The human body's blood glucose levels are inherently dynamic and constantly changing. They are influenced by various factors such as mood, diet, hydration, and exercise. Levels may be lower when you are calm and can rise when you are excited or stressed. Therefore, as long as there are no abnormal sharp fluctuations, variations in glucose readings at different times are within the normal range.

Common reasons include:

• Testing the same drop of blood twice:Blood exposed to air becomes oxidized, altering its actual composition, which often leads to a different result on the second test.

• Drawing blood consecutively from the same puncture site:After the first measurement, interstitial fluid may seep into the puncture site. The blood sample drawn second may contain more of this fluid, leading to a lower reading. Excessive squeezing can exacerbate this effect.

• Comparing blood from different hands or fingers at the same time:Blood glucose is a real-time fluctuating indicator, so this type of comparison is not recommended. If verification is needed, bring your glucose meter to the hospital to compare its reading with a venous blood biochemical test result.

The human body's blood glucose levels are inherently dynamic and constantly changing. They are influenced by various factors such as mood, diet, hydration, and exercise. Levels may be lower when you are calm and can rise when you are excited or stressed. Therefore, as long as there are no abnormal sharp fluctuations, variations in glucose readings at different times are within the normal range.

Common reasons include:

• Testing the same drop of blood twice: Blood exposed to air becomes oxidized, altering its actual composition, which often leads to a different result on the second test.

• Drawing blood consecutively from the same puncture site:After the first measurement, interstitial fluid may seep into the puncture site. The blood sample drawn second may contain more of this fluid, leading to a lower reading. Excessive squeezing can exacerbate this effect.

• Comparing blood from different hands or fingers at the same time:Blood glucose is a real-time fluctuating indicator, so this type of comparison is not recommended. If verification is needed, bring your glucose meter to the hospital to compare its reading with a venous blood biochemical test result.

The human body's blood glucose levels are inherently dynamic and constantly changing. They are influenced by various factors such as mood, diet, hydration, and exercise. Levels may be lower when you are calm and can rise when you are excited or stressed. Therefore, as long as there are no abnormal sharp fluctuations, variations in glucose readings at different times are within the normal range.

Common reasons include:

• Testing the same drop of blood twice:Blood exposed to air becomes oxidized, altering its actual composition, which often leads to a different result on the second test.

• Drawing blood consecutively from the same puncture site:After the first measurement, interstitial fluid may seep into the puncture site. The blood sample drawn second may contain more of this fluid, leading to a lower reading. Excessive squeezing can exacerbate this effect.

• Comparing blood from different hands or fingers at the same time:Blood glucose is a real-time fluctuating indicator, so this type of comparison is not recommended. If verification is needed, bring your glucose meter to the hospital to compare its reading with a venous blood biochemical test result.

The Anytime CGM system is a continuous glucose monitoring system that automatically sends glucose readings every 3 minutes to your Anytime APP or receiver, so you can act faster to avoid hypoglycemia.

Interstitial fluid glucose measurements are taken from the fluid within tissue while blood glucose measurements are taken directly from the blood.

Sensor glucose values, which are based on interstitial fluid glucose levels, can be different from blood glucose levels (fingersticks), particularly during times when your blood glucose is changing quickly. For example, after eating, taking insulin, or exercising. When glucose levels are falling quickly, glucose readings from the sensor may be higher than blood glucose levels. On the other hand, when glucose levels are rising quickly, glucose readings from the sensor may be lower than blood glucose levels.